17780-72-2
Chemical Structure
Clorgyline
Synonym(s): M&B 9302
- CAS No.: 17780-72-2
- Formula:C13H15Cl2NO
- Molecular Weight:272.17
IUPAC Name: N-(3-(2,4-dichlorophenoxy)propyl)-N-methylprop-2-yn-1-amine
InChIKey: BTFHLQRNAMSNLC-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C(Cl)=C1)OCCCN(CC#C)C
Biological Activity: Clorgyline (M&B 9302) is an orally active, blood-brain barrier permeable and selective monoamine oxidase A (MAO-A) inhibitor. Clorgyline's selective inhibition of MAO-A leads to reduced metabolism of neurotransmitters such as serotonin (5-hydroxytryptamine), which accumulates in the brain. Clorgyline can be used in the study of depression and neurodegenerative diseases[1].
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Clorgyline | 99.76% | Clorgyline (M&B 9302) is an orally active, blood-brain barrier permeable and selective monoamine oxidase A (MAO-A) inhibitor. Clorgyline's selective inhibition of MAO-A leads to reduced metabolism of neurotransmitters such as serotonin (5-hydroxytryptamine), which accumulates in the brain. Clorgyline can be used in the study of depression and neurodegenerative diseases. | ||||||||||||||||||||
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Keywords