1781882-72-1
Chemical Structure
SB-747651A dihydrochloride
- CAS No.: 1781882-72-1
- Formula:C16H24Cl2N8O
- Molecular Weight:415.32
IUPAC Name: 4-(1-ethyl-7-((piperidin-4-ylamino)methyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride
InChIKey: NRRCQHARLPNLHJ-UHFFFAOYSA-N
SMILES: NC1=NON=C1C(N2CC)=NC3=C2C(CNC4CCNCC4)=CN=C3.[H]Cl.[H]Cl
Biological Activity: SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC50 of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research[1].
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SB-747651A dihydrochloride | 99.14% | SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC50 of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research. | ||||||||||||||||||||
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SB-747651A dihydrochloride (Standard) | ≥98% | SB-747651A (dihydrochloride) (Standard) is the analytical standard of SB-747651A (dihydrochloride). This product is intended for research and analytical applications. SB-747651A dihydrochloride is an ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor with an IC50 of 11 nM. SB-747651A dihydrochloride also inhibits PRK2, RSK1, p70S6K and ROCK-II. SB-747651A dihydrochloride can be used for inflammation research. | ||||||||||||||||||||
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Similarity Score 0.97
HY-114038SB-747651A -
Similarity Score 0.68
HY-108518RSB-772077B dihydrochloride (Standard) -
Similarity Score 0.66
HY-123958SB772077B -
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HY-10249GSK-690693 -
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HY-114005SB-734117 -
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HY-10249DRAKT Kinase Inhibitor hydrochloride (Standard) -
Similarity Score 0.51
HY-10249AAKT Kinase Inhibitor -
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HY-130305GSK-938890A -
Similarity Score 0.47
HY-130305AGSK-943949A -
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