178359-31-4
Chemical Structure
Brazzein
- CAS No.: 178359-31-4
- Formula:C276H410N76O89S8
- Molecular Weight:6473.18
SMILES: O=C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=C(C=C1)O)C(O)=O)=O)=O)NC2=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N5[C@@H](CCC5)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H]8CCC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC9=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@H]%10[C@@H](C)CC)=O)NC8=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(O)=O)C(N[C@H]2CC%12=CC=C(C=C%12)O)=O)=O)NC%10=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC%13=CNC=N%13)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC(N[C@H]9CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC%14)NC%14=O
Biological Activity:
Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities.
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Brazzein | Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities. Brazzein inhibits COX-2 with an IC50 of 12.62 μM. Brazzein exhibits strong antioxidant effects, showing ABTS radical scavenging activity (IC50 = 12.55 μM). Brazzein shows no antibacterial or antifungal activity. Brazzein can be used for the research of obesity, metabolic disorder, inflammation. |
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- [1]. Chung JH, et al. Antioxidant, anti-inflammatory, and anti-allergic activities of the sweet-tasting protein brazzein. Food Chem. 2018;267:163-169. [Content Brief]
- [2]. Martinez Raquel, et al. Brazzein as a sustainable alternative to sugar: production, perception, and public health impact. J Appl Biotechnol Bioeng. 2025;12(1):45-48.
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