Brazzein
Brazzein is a functional sweetener with antioxidant, anti-inflammatory, and anti-allergic activities.
For research use only. We do not sell to patients.
- CAS No.: 178359-31-4
- Formula: C276H410N76O89S8
- Molecular Weight:6473.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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COX-2 12.62 μM (IC50) |
Brazzein (15-30 μM) shows strong ABTS radical scavenging activity with an IC50 of 12.55 μM in cell-free conditions[1].
Brazzein (15-30 μM; 30 min) shows weaker DPPH radical scavenging activity compared to ABTS, with an IC50 > 30 μM in cell-free conditions[1].
Brazzein (3-25 μM) inhibits human COX-2 activity with an IC50 of 12.62 μM in cell-free conditions[1].
Brazzein (1–15 μM) shows weak anti-inflammatory activity in RAW 264.7 cells, with an IC50 > 15 μM for NO production inhibition[1].
Brazzein (1-15 μM) has no cytotoxic effect on RAW 264.7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 178359-31-4
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Molecular Weight 6473.18
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Formula C276H410N76O89S8
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Sequence
Glp-Asp-Lys-Cys-Lys-Lys-Val-Tyr-Glu-Asn-Tyr-Pro-Val-Ser-Lys-Cys-Gln-Leu-Ala-Asn-Gln-Cys-Asn-Tyr-Asp-Cys-Lys-Leu-Asp-Lys-His-Ala-Arg-Ser-Gly-Glu-Cys-Phe-Tyr-Asp-Glu-Lys-Arg-Asn-Leu-Gln-Cys-Ile-Cys-Asp-Tyr-Cys-Glu-Tyr (disulfide bridge:Cys4-Cys52,Cys16-Cys37,Cys22-Cys47,Cys26-Cys49)
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Sequence Shortening
Glp-DKCKKVYENYPVSKCQLANQCNYDCKLDKHARSGECFYDEKRNLQCICDYCEY (disulfide bridge:Cys4-Cys52,Cys16-Cys37,Cys22-Cys47,Cys26-Cys49)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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