1786401-70-4
1786401-70-4
Chemical Structure
(R)-I-BET762 carboxylic acid
Synonym(s): (R)-Molibresib carboxylic acid; (R)-GSK525762A carboxylic acid; (R)-PROTAC BRD4-binding moiety 2
- CAS No.: 1786401-70-4
- Formula:C20H17ClN4O3
- Molecular Weight:396.83
InChIKey: VEIZLTSJCDOIBH-MRXNPFEDSA-N
SMILES: CC1=NN=C2[C@@H](CC(O)=O)N=C(C3=CC=C(Cl)C=C3)C4=C(C=CC(OC)=C4)N21
Biological Activity: (R)-I-BET762 carboxylic acid, the R-enantiomer of I-BET762 carboxylic acid (HY-107443). I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid is a BRD4 inhibitor with a pIC50 value of 5.1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-I-BET762 carboxylic acid | 99.50% | (R)-I-BET762 carboxylic acid, the R-enantiomer of I-BET762 carboxylic acid (HY-107443). I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid is a BRD4 inhibitor with a pIC50 value of 5.1. | ||||||||||||||||||||
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(R)-I-BET762 carboxylic acid (Standard) | ≥98% | (R)-I-BET762 carboxylic acid (Standard) is the analytical standard of (R)-I-BET762 carboxylic acid (HY-107443A). This product is intended for research and analytical applications. (R)-I-BET762 carboxylic acid, the R-enantiomer of I-BET762 carboxylic acid (HY-107443). I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid is a BRD4 inhibitor with a pIC50 value of 5.1. | ||||||||||||||||||||
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References
