1832646-52-2
Chemical Structure
GLS1 Inhibitor-1
- CAS No.: 1832646-52-2
- Formula:C19H21N7O2S
- Molecular Weight:411.48
IUPAC Name: (S)-2-methoxy-2-phenyl-N-(5-(((R)-1-(pyridazin-3-yl)pyrrolidin-3-yl)amino)-1,3,4-thiadiazol-2-yl)acetamide
InChIKey: KLQLQDLJJUAEGT-ZBFHGGJFSA-N
SMILES: O=C([C@H](C1=CC=CC=C1)OC)NC2=NN=C(S2)N[C@H]3CN(C4=CC=CN=N4)CC3
Biological Activity: GLS1 Inhibitor-1 is an orally active, allosteric, selective GLS1 inhibitor with an IC50 of 0.021 µM for GLS1 and an IC50 of 0.051 µM for the GLS1 GAC splice variant. GLS1 Inhibitor-1 increases glutamine and decreases glutamate and aspartate. GLS1 Inhibitor-1 exhibits anticancer activity against non-small cell lung cancer. GLS1 Inhibitor-1 can be used for research on non-small cell lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GLS1 Inhibitor-1 | 99.61% | GLS1 Inhibitor-1 is an orally active, allosteric, selective GLS1 inhibitor with an IC50 of 0.021 µM for GLS1 and an IC50 of 0.051 µM for the GLS1 GAC splice variant. GLS1 Inhibitor-1 increases glutamine and decreases glutamate and aspartate. GLS1 Inhibitor-1 exhibits anticancer activity against non-small cell lung cancer. GLS1 Inhibitor-1 can be used for research on non-small cell lung cancer. | ||||||||||||||||||||
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