184147-65-7
184147-65-7
Chemical Structure
FR-181074
- CAS No.: 184147-65-7
- Formula:C23H25ClN2O2
- Molecular Weight:396.91
IUPAC Name: 1-(2-chlorobenzyl)-3-isobutyryl-2-propyl-1H-indole-6-carboxamide
InChIKey: WWXPHRJCGKFIQK-UHFFFAOYSA-N
SMILES: O=C(C1=CC(N(CC2=C(Cl)C=CC=C2)C(CCC)=C3C(C(C)C)=O)=C3C=C1)N
Biological Activity: FR-181074 is a selective and orally active PDE V inhibitor. FR-181074 can specifically block PDE V to inhibit the degradation of cyclic guanosine monophosphate (cGMP) in order to relax smooth muscle. FR-181074 can be used for the researches of cardiovascular disease and endocrinology, such as hypertension and erectile dysfunction[1].
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FR-181074 | FR-181074 is a selective and orally active PDE V inhibitor. FR-181074 can specifically block PDE V to inhibit the degradation of cyclic guanosine monophosphate (cGMP) in order to relax smooth muscle. FR-181074 can be used for the researches of cardiovascular disease and endocrinology, such as hypertension and erectile dysfunction. | |||||||||||||||||||||
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