1890169-95-5
1890169-95-5
Chemical Structure
UPGL00004
- CAS No.: 1890169-95-5
- Formula:C25H26N8O2S2
- Molecular Weight:534.66
IUPAC Name: 2-phenyl-N-(5-(4-((5-(2-phenylacetamido)-1,3,4-thiadiazol-2-yl)amino)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)acetamide
InChIKey: MRYCNTHLPRENBA-UHFFFAOYSA-N
SMILES: O=C(NC1=NN=C(N2CCC(NC3=NN=C(NC(CC4=CC=CC=C4)=O)S3)CC2)S1)CC5=CC=CC=C5
Biological Activity: UPGL00004 is a potent allosteric glutaminase C (GAC) inhibitor (IC50=29 nM; Kd=27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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UPGL00004 | 98.0% | UPGL00004 is a potent allosteric glutaminase C (GAC) inhibitor (IC50=29 nM; Kd=27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.67
HY-146658Glutaminase-IN-4 -
Similarity Score 0.66
HY-12683RBPTES (Standard) -
Similarity Score 0.65
HY-146617GLS1 Inhibitor-4 -
Similarity Score 0.61
HY-149602Glutaminase C-IN-2 -
Similarity Score 0.59
HY-152207LWG-301 -
Similarity Score 0.56
HY-151434GLS1 Inhibitor-6 -
Similarity Score 0.53
HY-136704GLS1 Inhibitor-1 -
Similarity Score 0.51
HY-163901E6-272 -
Similarity Score 0.48
HY-143288NTPDase2-IN-1 -
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