192581-24-1
Chemical Structure
BIIL-260 hydrochloride
- CAS No.: 192581-24-1
- Formula:C30H31ClN2O3
- Molecular Weight:503.03
IUPAC Name: 4-((3-((4-(2-(4-hydroxyphenyl)propan-2-yl)phenoxy)methyl)benzyl)oxy)benzimidamide hydrochloride
InChIKey: KYFHIWXKXUSXKB-UHFFFAOYSA-N
SMILES: N=C(C1=CC=C(OCC2=CC=CC(COC3=CC=C(C(C)(C4=CC=C(O)C=C4)C)C=C3)=C2)C=C1)N.[H]Cl
Biological Activity: BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM[1].
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BIIL-260 hydrochloride | 99.44% | BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM. | ||||||||||||||||||||
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