19360-72-6
Chemical Structure
GB-1a
Synonym(s): Biflavanone GB-1a
- CAS No.: 19360-72-6
- Formula:C30H22O10
- Molecular Weight:542.49
IUPAC Name: (2S,2'S,3R)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,8'-bichromane]-4,4'-dione
InChIKey: MXEIKUWMKSYEII-DETITRACSA-N
SMILES: O=C1[C@@](C2=C3C(C(C[C@](C4=CC=C(C=C4)O)([H])O3)=O)=C(C=C2O)O)([H])[C@](C5=CC=C(C=C5)O)([H])OC6=CC(O)=CC(O)=C61
Biological Activity: GB-1a (Biflavanone GB-1a) is a biflavanone HIV-1 reverse transcriptase inhibitor (IC50=236 μM), with an EC50 of 38.0 μM for HIV-1 replication. GB-1a can block the conversion of HIV-1 genomic RNA to DNA and can be used in research related to AIDS (HIV-1 infection). GB-1a can be naturally extracted from the heartwood of Garcinia multiflora Champ[1].
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GB-1a | GB-1a (Biflavanone GB-1a) is a biflavanone HIV-1 reverse transcriptase inhibitor (IC50=236 μM), with an EC50 of 38.0 μM for HIV-1 replication. GB-1a can block the conversion of HIV-1 genomic RNA to DNA and can be used in research related to AIDS (HIV-1 infection). GB-1a can be naturally extracted from the heartwood of Garcinia multiflora Champ. | |||||||||||||||||||||
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