2032-65-7
Chemical Structure
Methiocarb
Synonym(s): Mercaptodimethur
- CAS No.: 2032-65-7
- Formula:C11H15NO2S
- Molecular Weight:225.31
IUPAC Name: 3,5-dimethyl-4-(methylthio)phenyl methylcarbamate
InChIKey: YFBPRJGDJKVWAH-UHFFFAOYSA-N
SMILES: O=C(NC)OC1=CC(C)=C(SC)C(C)=C1
Biological Activity: Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals[1][2].
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Methiocarb | Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals. | |||||||||||||||||||||
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Methiocarb-d3 | Methiocarb-d3 is the deuterium labeled Methiocarb (HY-124920). Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals. | |||||||||||||||||||||
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- [1]. Tütüncü E, et al. Investigation of the toxic effects of a carbamate insecticide methiocarb in Allium cepa L. Cytologia, 2019, 84(2): 113-117.
- [2]. Ozden S, et al. Effects of methiocarb on lipid peroxidation and glutathione level in rat tissues. Drug Chem Toxicol. 2010;33(1):50-54. [Content Brief]
Keywords