2070009-55-9
Chemical Structure
PF-2771
- CAS No.: 2070009-55-9
- Formula:C29H36ClN5O4
- Molecular Weight:554.08
IUPAC Name: (S)-N-(1-(4-(2-acetyl-1-methyl-1H-imidazol-4-yl)phenyl)-3-(2-(dimethylamino)acetamido)propan-2-yl)-3-chloro-4-isopropoxybenzamide
InChIKey: VHBJNUOZEQTSNN-QHCPKHFHSA-N
SMILES: ClC1=CC(C(N[C@@H](CC2=CC=C(C3=CN(C)C(C(C)=O)=N3)C=C2)CNC(CN(C)C)=O)=O)=CC=C1OC(C)C
Biological Activity: PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor, inhibiting CENP-E motor activity with an IC50 of 16.1 nM; PF-2771 is used as an anticancer agent.
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PF-2771 | 99.66% | PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor, inhibiting CENP-E motor activity with an IC50 of 16.1 nM; PF-2771 is used as an anticancer agent. | ||||||||||||||||||||
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Keywords