2086257-77-2
2086257-77-2
Chemical Structure
VBIT-4
- CAS 番号: 2086257-77-2
- Formula:C21H23ClF3N3O3
- Molecular Weight:457.87
IUPAC Name: N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide
InChIKey: QYSQXVAEFPWMEM-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(Cl)C=C1)CC(CO)N2CCN(C3=CC=C(OC(F)(F)F)C=C3)CC2
Biological Activity: VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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VBIT-4 | 99.86% | VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases. | ||||||||||||||||||||
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VBIT-4 (Standard) | ≥98% | VBIT-4 (Standard) is the analytical standard of VBIT-4 (HY-129122). This product is intended for research and analytical applications. VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.65
HY-135571VBIT-3 -
Similarity Score 0.61
HY-111217AKOS-22 -
Similarity Score 0.58
HY-W699179Itraconazole impurity 16 -
Similarity Score 0.57
HY-157563Dopamine D4 receptor ligand 2 -
Similarity Score 0.55
HY-10313ZD 2486 -
Similarity Score 0.54
HY-Z9706Itraconazole impurity 18 -
Similarity Score 0.53
HY-146202PDE4B/7A-IN-2 -
Similarity Score 0.53
HY-W011532Itraconazole impurity 15 -
Similarity Score 0.53
HY-148825NP10679 -
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