2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE4B/7A-IN-2

5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with PDE4B/PDE7A inhibitory activity (PDE4B IC50 = 80.4 μM; PDE7A IC50 = 151.3 μM) , its antidepressant like effect is stronger than that of escitalopram as a reference agent.

For research use only. We do not sell to patients.

PDE4B/7A-IN-2 Chemical Structure

PDE4B/7A-IN-2 Chemical Structure

CAS No. : 2511632-55-4

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PDE4B/7A-IN-2 Related Antibodies

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

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Description

5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with PDE4B/PDE7A inhibitory activity (PDE4B IC50 = 80.4 μM; PDE7A IC50 = 151.3 μM) , its antidepressant like effect is stronger than that of escitalopram as a reference agent.

IC50 & Target

PDE4

 

PDE7

 

Molecular Weight

409.56

Formula

C25H35N3O2
CAS No.
SMILES

COC1=C(C=CC=C1)N2CCN(CC2)CCCCC(NC3=CC=C(C=C3)C(C)C)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PDE4B/7A-IN-2 Related Classifications

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDE4B/7A-IN-22511632-55-4Phosphodiesterase (PDE)Inhibitorinhibitorinhibit

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