2103278-86-8
Chemical Structure
Bofutrelvir
Synonym(s): FB2001
- CAS No.: 2103278-86-8
- Formula:C25H32N4O4
- Molecular Weight:452.55
IUPAC Name: N-((S)-3-cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)-1H-indole-2-carboxamide
InChIKey: HPKJGHVHQWJOOT-ZJOUEHCJSA-N
SMILES: O=C(C(N1)=CC2=C1C=CC=C2)N[C@@H](CC3CCCCC3)C(N[C@H](C=O)C[C@H]4C(NCC4)=O)=O
Biological Activity: Bofutrelvir (FB2001) is a SARS-CoV-2 main protease Mpro inhibitor with an IC50 value of 53 nM and an EC50 value of 0.53 μM. Bofutrelvir exhibits potent antiviral efficacy against several current SARS-CoV-2 variants with EC50 values of 0.26-0.42 μM. Bofutrelvir has an additive antiviral effect when combined with Remdesivir (HY-104077)[1][2].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Bofutrelvir | 95.0% | Bofutrelvir (FB2001) is a SARS-CoV-2 main protease Mpro inhibitor with an IC50 value of 53 nM and an EC50 value of 0.53 μM. Bofutrelvir exhibits potent antiviral efficacy against several current SARS-CoV-2 variants with EC50 values of 0.26-0.42 μM. Bofutrelvir has an additive antiviral effect when combined with Remdesivir (HY-104077). | ||||||||||||||||||||
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-
Similarity Score 0.82
HY-160594SARS 3CLpro-IN-2 -
Similarity Score 0.72
HY-136606SARS-CoV MPro-IN-1 -
Similarity Score 0.72
HY-176211SARS-CoV-2 Mpro-IN-45 -
Similarity Score 0.68
HY-153228Pomotrelvir -
Similarity Score 0.65
HY-156655Olgotrelvir -
Similarity Score 0.63
HY-156655AOlgotrelvir sodium -
Similarity Score 0.60
HY-137048PF-00835231 -
Similarity Score 0.56
HY-138078Lufotrelvir -
Similarity Score 0.53
HY-145435SARS-CoV-2-IN-12 -
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