2140-71-8
2140-71-8
Chemical Structure
2'-O-Methylguanosine
- CAS No.: 2140-71-8
- Formula:C11H15N5O5
- Molecular Weight:297.27
IUPAC Name: 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: OVYNGSFVYRPRCG-KQYNXXCUSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O[C@@H]1CO
Biological Activity: 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells[1][2].
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2'-O-Methylguanosine | 99.81% | 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells. | ||||||||||||||||||||
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2'-O-Methylguanosine (Standard) | 99.06% | 2'-O-Methylguanosine (Standard) is the analytical standard of 2'-O-Methylguanosine (HY-W013260). This product is intended for research and analytical applications. 2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells. | ||||||||||||||||||||
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References
- [1]. B C Persson, et al. The spoU gene of Escherichia coli, the fourth gene of the spoT operon, is essential for tRNA (Gm18) 2'-O-methyltransferase activity. Nucleic Acids Res. 1997 Oct 15;25(20):4093-7. [Content Brief]
- [2]. T Mori, et al. Isolation and identification of apoptosis inducing nucleosides from CD57(+)HLA-DRbright natural suppressor cell line. Biochem Biophys Res Commun. 1998 Oct 20;251(2):416-22. [Content Brief]
