2140-77-4
2140-77-4
Chemical Structure
N2-Methylguanosine
- CAS No.: 2140-77-4
- Formula:C11H15N5O5
- Molecular Weight:297.27
IUPAC Name: 9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(methylamino)-1,9-dihydro-6H-purin-6-one
InChIKey: SLEHROROQDYRAW-KQYNXXCUSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(NC)NC3=O)O1
Biological Activity: N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA[1][2][3].
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N2-Methylguanosine | 98.58% | N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA. | ||||||||||||||||||||
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N2-Methylguanosine (Standard) | ≥98% | N2-Methylguanosine (Standard) is the analytical standard of N2-Methylguanosine (HY-111647). This product is intended for research and analytical applications. N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA. | ||||||||||||||||||||
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N2-Methylguanosine-d3 | N2-Methylguanosine-d3 is deuterium labeled N2-Methylguanosine (HY-111647). N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.91
HY-152613N2-Ethylguanosine -
Similarity Score 0.88
HY-113137N2,N2-Dimethylguanosine -
Similarity Score 0.87
HY-1526739-(β-D-Xylofuranosyl)guanine -
Similarity Score 0.87
HY-154536Alpha-Guanosine -
Similarity Score 0.87
HY-N0097A9-β-D-Arabinofuranosylguanine -
Similarity Score 0.87
HY-N0097RGuanosine (Standard) -
Similarity Score 0.87
HY-N0097S3Guanosine-15N5 -
Similarity Score 0.87
HY-N0097S6Guanosine-13C10,15N5 -
Similarity Score 0.87
HY-W755003Guanosine-13C5 -
Explore the MedChemAI to find more analogs
References
- [1]. Ginell SL, et al. Conformation of N2-methylguanosine, a modified nucleoside of tRNA. Biochem Biophys Res Commun. 1978 Oct 30;84(4):886-94. [Content Brief]
- [2]. Chheda GB, et al. Nucleosides in human urine. I. Isolation and identification of N2-dimethylguanosine, 1-methylinosine, and N2-methylguanosine from normal human urine. J Pharm Sci. 1969 Jan;58(1):75-8. [Content Brief]
- [3]. Pallan PS, et al. Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs. RNA. 2008 Oct;14(10):2125-35. doi: 10.1261/rna.1078508IF: 4.2 Q2 . Epub 2008 Sep 4. Erratum in: RNA. 2008 Nov;14(11):2452. [Content Brief]
