219986-51-3
Chemical Structure
Cimicifugic acid D
Synonym(s): 2-Caffeoylpiscidic acid
- CAS No.: 219986-51-3
- Formula:C20H18O10
- Molecular Weight:418.35
SMILES: OC(C=C1)=CC=C1C[C@@](C(O)=O)(O)[C@@H](C(O)=O)OC(/C=C/C2=CC(O)=C(C=C2)O)=O
Biological Activity: Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyltartaric acid ester that induces vasodilation of precontracted rat aortic strips and endothelium-independent relaxation mechanism. Cimicifugic acid D inhibits extracellular Ca2+ influx through receptor-operated Ca2+ channels (ROC) in Norepinephrine (HY-13715)-induced contraction of rat aortic strips, without affecting voltage-dependent Ca2+ channels (VDC) or K+-induced contractions[1].
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Cimicifugic acid D | Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyltartaric acid ester that induces vasodilation of precontracted rat aortic strips and endothelium-independent relaxation mechanism. Cimicifugic acid D inhibits extracellular Ca2+ influx through receptor-operated Ca2+ channels (ROC) in Norepinephrine (HY-13715)-induced contraction of rat aortic strips, without affecting voltage-dependent Ca2+ channels (VDC) or K+-induced contractions. | |||||||||||||||||||||
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