Cimicifugic acid D
Cimicifugic acid D (2-Caffeoylpiscidic acid) is a benzyltartaric acid ester that induces vasodilation of precontracted rat aortic strips and endothelium-independent relaxation mechanism. Cimicifugic acid D inhibits extracellular Ca2+ influx through receptor-operated Ca2+ channels (ROC) in Norepinephrine (HY-13715)-induced contraction of rat aortic strips, without affecting voltage-dependent Ca2+ channels (VDC) or K+-induced contractions.
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- CAS 番号: 219986-51-3
- 分子式: C20H18O10
- 分子量:418.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
製品説明
体外実験
Cimicifugic acid D (300 μM; 1 h; rat aortic strips) causes relaxation of Norepinephrine-precontracted aortic strips, and reduces Norepinephrine-induced concentration-dependent contraction[1].
Cimicifugic acid D (30 μM; 1 h; rat aortic strips) inhibits Ca2+-induced contraction in Norepinephrine-pretreated aortic strips[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 219986-51-3
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分子量 418.35
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分子式 C20H18O10
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SMILES
OC(C=C1)=CC=C1C[C@@](C(O)=O)(O)[C@@H](C(O)=O)OC(/C=C/C2=CC(O)=C(C=C2)O)=O
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別名
2-Caffeoylpiscidic acid
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)