2201082-98-4
2201082-98-4
Chemical Structure
I-BET787
- CAS No.: 2201082-98-4
- Formula:C16H20ClN3O2
- Molecular Weight:321.80
InChIKey: UEHOXEWBUJAXSW-UHFFFAOYSA-N
SMILES: CC1=CC(C2=NC(Cl)=CN2CC3CCOCC3)=CN(C1=O)C
Biological Activity: I-BET787 is a orally active BET bromine domain inhibitor with pIC50s of 7.1 and 5.9 for BRD4 BD1 and BRD4 BD2, respectively. I-BET787 has anti-inflammatory activity in mice[1].
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I-BET787 | 99.88% | I-BET787 is a orally active BET bromine domain inhibitor with pIC50s of 7.1 and 5.9 for BRD4 BD1 and BRD4 BD2, respectively. I-BET787 has anti-inflammatory activity in mice. | ||||||||||||||||||||
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References
Keywords
