2215852-91-6
Chemical Structure
GSK3395879
- CAS No.: 2215852-91-6
- Formula:C20H15F4N3O5S
- Molecular Weight:485.41
IUPAC Name: 4-(((3S,4R)-1-((2-cyano-4-(trifluoromethyl)phenyl)sulfonyl)-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl)oxy)-2-fluorobenzonitrile
InChIKey: RAYCYIKGBWRQBC-RBUKOAKNSA-N
SMILES: FC1=C(C#N)C=CC(O[C@@H]2[C@@](CO)(O)CN(S(C3=C(C#N)C=C(C(F)(F)F)C=C3)(=O)=O)C2)=C1
Biological Activity: GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4[1].
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GSK3395879 | GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4. | |||||||||||||||||||||
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Keywords