2221707-61-3
2221707-61-3
Chemical Structure
PTP1B-IN-24
- CAS No.: 2221707-61-3
- Formula:C22H16N2O5S
- Molecular Weight:420.44
InChIKey: UGMVFZBUJLCYOC-ZDLGFXPLSA-N
SMILES: O=C(S/1)N(CC(NC2=CC=C(C)C=C2)=O)C(C1=C\C3=COC4=CC=CC=C4C3=O)=O
Biological Activity: PTP1B-IN-24 (Compound 9) is a reversible PTP1B inhibitor with an IC50 value of 1.4 μM, and PTP1B-IN-24 can enhance the thermal stability of PTP1B. PTP1B-IN-24 can restore PA- (HY-N0830) induced insulin resistance by increasing the phosphorylation levels of IRS1 and AKT[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PTP1B-IN-24 | 98.46% | PTP1B-IN-24 (Compound 9) is a reversible PTP1B inhibitor with an IC50 value of 1.4 μM, and PTP1B-IN-24 can enhance the thermal stability of PTP1B. PTP1B-IN-24 can restore PA- (HY-N0830) induced insulin resistance by increasing the phosphorylation levels of IRS1 and AKT. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
