2227350-99-2
Chemical Structure
Val-Cit-PAB-Exatecan
Synonym(s): Val-Cit-PAB-DX8951
- No. CAS: 2227350-99-2
- Formula:C43H49FN8O9
- Molecular Weight:840.90
IUPAC Name: 4-((S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanamido)benzyl ((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)carbamate
InChIKey: JRIHOFFBVWRHMO-NMNMEXSISA-N
SMILES: CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O
Biological Activity: Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Val-Cit-PAB-Exatecan | 98.26% | Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker. | ||||||||||||||||||||
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Similarity Score 0.94
HY-153031AVal-Cit-PAB-Exatecan TFA -
Similarity Score 0.89
HY-171931Aminocaproyl-Val-Cit-PABC-Exatecan -
Similarity Score 0.89
HY-147095Val-Ala-PABC-Exatecan -
Similarity Score 0.88
HY-147095AVal-Ala-PABC-Exatecan trifluoroacetate -
Similarity Score 0.87
HY-158137Val-Cit-PAB-DEA-Dxd -
Similarity Score 0.85
HY-171931AAminocaproyl-Val-Cit-PABC-Exatecan TFA -
Similarity Score 0.84
HY-145929MC-Val-Cit-PAB-Exatecan -
Similarity Score 0.84
HY-160756Val-Cit-Exatecan -
Similarity Score 0.83
HY-186185OSu-Val-Cit-PAB-Exa -
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