2247236-59-3
2247236-59-3
Chemical Structure
BY27
- CAS No.: 2247236-59-3
- Formula:C22H21ClN6
- Molecular Weight:404.90
IUPAC Name: (R)-N-(4-chlorophenyl)-1-methyl-8-(1-methyl-1H-pyrazol-4-yl)-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[4,3-a]azepin-6-amine
InChIKey: MDRXOFSNECSECW-HXUWFJFHSA-N
SMILES: CN1N=CC(C2=CC=C(N3C(CC[C@H]4NC5=CC=C(Cl)C=C5)=NN=C3C)C4=C2)=C1
Biological Activity: BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity[1].
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BY27 | BY27 is a potent and selective BET BD2 inhibitor, shows 38, 5, 7, and 21-fold BD1/BD2 selectivity for BRD2, BRD3, BRD4, and BRDT. Anti-cancer activity. | |||||||||||||||||||||
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