2249944-99-6

PROTAC MDM2 Degrader-2 Chemical Structure
2249944-99-6

Chemical Structure

PROTAC MDM2 Degrader-2

  • CAS No.: 2249944-99-6
  • Formula:C70H76Cl4N10O12
  • Molecular Weight:1391.22

IUPAC Name: N,N'-((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(2-(4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetamide)

InChIKey: WZLSSHVSGKCEKQ-AKOOKZATSA-N

SMILES: O=C(N1CC(N(CC(NCCOCCOCCNC(CN2C(CN(C(N3[C@@H](C4=CC=C(Cl)C=C4)[C@@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@@H](C8=CC=C(Cl)C=C8)[C@@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C

Biological Activity: PROTAC MDM2 Degrader-2 is an MDM2 PROTAC degrader. PROTAC MDM2 Degrader-2 can induce the self-ubiquitination and degradation of MDM2, thereby upregulating the level of p53 protein. PROTAC MDM2 Degrader-2 has anti-tumor activity and can be used in the study of cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-128841 		PROTAC MDM2 Degrader-2 95.01% PROTAC MDM2 Degrader-2 is an MDM2 PROTAC degrader. PROTAC MDM2 Degrader-2 can induce the self-ubiquitination and degradation of MDM2, thereby upregulating the level of p53 protein. PROTAC MDM2 Degrader-2 has anti-tumor activity and can be used in the study of cancer.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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