1. PROTAC
    Apoptosis
  2. PROTAC
    MDM-2/p53
  3. PROTAC MDM2 Degrader-2

PROTAC MDM2 Degrader-2 

Cat. No.: HY-128841
Handling Instructions

PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase.

For research use only. We do not sell to patients.

PROTAC MDM2 Degrader-2 Chemical Structure

PROTAC MDM2 Degrader-2 Chemical Structure

CAS No. : 2249944-99-6

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Description

PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].

IC50 & Target

MDM2

 

Molecular Weight

1391.22

Formula

C₇₀H₇₆Cl₄N₁₀O₁₂

CAS No.

2249944-99-6

SMILES

O=C(N1CC(N(CC(NCCOCCOCCNC(CN2C(CN(C(N3[[email protected]@H](C4=CC=C(Cl)C=C4)[[email protected]@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[[email protected]@H](C8=CC=C(Cl)C=C8)[[email protected]@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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PROTAC MDM2 Degrader-2
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