2310286-45-2
2310286-45-2
Chemical Structure
IDO1/2-IN-1
- CAS No.: 2310286-45-2
- Formula:C16H18BrFN8O4
- Molecular Weight:485.27
IUPAC Name: (E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(4-((2-hydroxyethoxy)methyl)-1H-1,2,3-triazol-1-yl)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide
InChIKey: LFOXSTPPEXOYIT-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1Br)/N=C(C2=NON=C2NCCN3N=NC(COCCO)=C3)/NO
Biological Activity: IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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IDO1/2-IN-1 | 98.85% | IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-145280AIDO1/2-IN-1 hydrochloride -
Similarity Score 0.56
HY-79531IDO-IN-1 -
Similarity Score 0.52
HY-151093IDO2-IN-1 -
Similarity Score 0.51
HY-16987IDO-IN-3 -
Similarity Score 0.50
HY-15689REpacadostat (Standard) -
Similarity Score 0.50
HY-110387IDO-IN-9 -
Similarity Score 0.49
HY-15683IDO5L -
Similarity Score 0.48
HY-146215IDO1-IN-20 -
Similarity Score 0.48
HY-172233INCB-056868 -
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