2310286-45-2

IDO1/2-IN-1 Chemical Structure
2310286-45-2

Chemical Structure

IDO1/2-IN-1

  • CAS No.: 2310286-45-2
  • Formula:C16H18BrFN8O4
  • Molecular Weight:485.27

IUPAC Name: (E)-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-4-((2-(4-((2-hydroxyethoxy)methyl)-1H-1,2,3-triazol-1-yl)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide

InChIKey: LFOXSTPPEXOYIT-UHFFFAOYSA-N

SMILES: FC1=CC=C(C=C1Br)/N=C(C2=NON=C2NCCN3N=NC(COCCO)=C3)/NO

Biological Activity: IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active[1].

Cat. No. Product Name Purity Description Pricing
HY-145280 		IDO1/2-IN-1 98.06% IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC50s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active.
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