IDO-IN-3
Based on 1 Customer Validation
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
For research use only. We do not sell to patients.
- Purity: 98.97%
- CAS No.: 2070018-30-1
- Formula: C11H12BrFN6O2
- Molecular Weight:359.15
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Immunology/Inflammation Compound Library
HY-L007
-
Metabolism/Protease Compound Library
HY-L012
-
Anti-Cancer Compound Library
HY-L025
-
Small Molecule Immuno-Oncology Compound Library
HY-L031
-
Metabolic Enzyme Compound Library
HY-L146
-
Multi-Target Compound Library
HY-L176
-
MCE Bioactive Compound Library
HY-L001V
-
High-Throughput Bioactive Compound Library
HY-L205
Biological Activity
|
IDO-1 290 nM (IC50) |
IDO 98 nM (IC50, in HeLa cell) |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
98 nM
Compound: 4c
|
Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
|
[PMID: 28523098] |
Chemical Information
-
CAS No. 2070018-30-1
-
Appearance Solid
-
Molecular Weight 359.15
-
Formula C11H12BrFN6O2
-
Color White to off-white
-
SMILES
O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 27.5 mg/mL (76.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (282 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7844 mL | 13.9218 mL | 27.8435 mL | 69.6088 mL |
| 5 mM | 0.5569 mL | 2.7844 mL | 5.5687 mL | 13.9218 mL | |
| 10 mM | 0.2784 mL | 1.3922 mL | 2.7844 mL | 6.9609 mL | |
| 15 mM | 0.1856 mL | 0.9281 mL | 1.8562 mL | 4.6406 mL | |
| 20 mM | 0.1392 mL | 0.6961 mL | 1.3922 mL | 3.4804 mL | |
| 25 mM | 0.1114 mL | 0.5569 mL | 1.1137 mL | 2.7844 mL | |
| 30 mM | 0.0928 mL | 0.4641 mL | 0.9281 mL | 2.3203 mL | |
| 40 mM | 0.0696 mL | 0.3480 mL | 0.6961 mL | 1.7402 mL | |
| 50 mM | 0.0557 mL | 0.2784 mL | 0.5569 mL | 1.3922 mL | |
| 60 mM | 0.0464 mL | 0.2320 mL | 0.4641 mL | 1.1601 mL |
IDO-IN-3 Related Classifications
HY-16987 Related Classifications
Powered by Bioz