IDO-IN-3
Based on 1 Customer Validation
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.44%
- CAS. Nr.: 2070018-30-1
- Formel: C11H12BrFN6O2
- Molecular Weight:359.15
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-15689
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LinrodostatIDO1 Inhibitor -
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NavoximodIDO Inhibitor -
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IDO-IN-7 -
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Epacadostat (Standard)IDO1 Inhibitor -
HY-15683
IDO5LIDO Inhibitor -
HY-100771
PCC0208009IDO Inhibitor -
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IDO-IN-1IDO Inhibitor -
HY-111540
LY-3381916IDO1 Inhibitor -
HY-18769
BMS-978587IDO-1 Inhibitor
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
IDO-1 290 nM (IC50) |
IDO 98 nM (IC50, in HeLa cell) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
98 nM
Compound: 4c
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Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs
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[PMID: 28523098] |
In Vitro
Chemical Information
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CAS. Nr. 2070018-30-1
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Appearance Solid
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Molecular Weight 359.15
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Formel C11H12BrFN6O2
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Color White to off-white
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SMILES
O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 27.5 mg/mL (76.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (282 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7844 mL | 13.9218 mL | 27.8435 mL | 69.6088 mL |
| 5 mM | 0.5569 mL | 2.7844 mL | 5.5687 mL | 13.9218 mL | |
| 10 mM | 0.2784 mL | 1.3922 mL | 2.7844 mL | 6.9609 mL | |
| 15 mM | 0.1856 mL | 0.9281 mL | 1.8562 mL | 4.6406 mL | |
| 20 mM | 0.1392 mL | 0.6961 mL | 1.3922 mL | 3.4804 mL | |
| 25 mM | 0.1114 mL | 0.5569 mL | 1.1137 mL | 2.7844 mL | |
| 30 mM | 0.0928 mL | 0.4641 mL | 0.9281 mL | 2.3203 mL | |
| 40 mM | 0.0696 mL | 0.3480 mL | 0.6961 mL | 1.7402 mL | |
| 50 mM | 0.0557 mL | 0.2784 mL | 0.5569 mL | 1.3922 mL | |
| 60 mM | 0.0464 mL | 0.2320 mL | 0.4641 mL | 1.1601 mL |
IDO-IN-3 Related Classifications
HY-16987 Related Classifications
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