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Cat. No.: HY-172233

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INCB-056868

INCB-056868 is the metabolite M11 of Epacadostat (HY-15689). INCB-056868 can also serve as a substrate for BCRP. INCB-056868 is promising for research of metabolic diseases.

For research use only. We do not sell to patients.

CAS No.: 2252320-89-9
Formula: C₁₁H₁₃BrFN₇O₃S
Molecular Weight:422.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

INCB-056868 Chemical Structure

CAS No.: 2252320-89-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

INCB-056868 is the metabolite M11 of Epacadostat (HY-15689). INCB-056868 can also serve as a substrate for BCRP. INCB-056868 is promising for research of metabolic diseases^[1].

Chemical Information

CAS No. 2252320-89-9
Molecular Weight 422.23
Formula C₁₁H₁₃BrFN₇O₃S
SMILES

O=S(N)(NCCNC1=NON=C1C(NC2=CC=C(C(Br)=C2)F)=N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang Q, et al. In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions. Drug Metab Dispos. 2017 Jun;45(6):612-623. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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