2374782-07-5
Chemical Structure
FAPI-34
- CAS No.: 2374782-07-5
- Formula:C50H57F2N13O18
- Molecular Weight:1166.06
IUPAC Name: (3S,3'S)-3,3'-((2,2'-((((2-(4-(3-((4-((2-((S)-2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy)propyl)piperazin-1-yl)-2-oxoethyl)azanediyl)bis(methylene))bis(1H-imidazole-2,1-diyl))bis(acetyl))bis(azanediyl))bis(propane-1,1,3-tricarboxylic acid)
InChIKey: FPOZMWSPTRNDPQ-UVXHQIPUSA-N
SMILES: O=C(C1=CC=NC(C=C2)=C1C=C2OCCCN(CC3)CCN3C(CN(CC4=NC=CN4CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)CC5=NC=CN5CC(N[C@H](C(O)=O)CC(C(O)=O)C(O)=O)=O)=O)NCC(N(CC6(F)F)[C@@H](C6)C#N)=O
Biological Activity: FAPI-34 is a SPECT imaging agent targeting FAP. FAPI-34 specifically binds to FAP, is highly internalized by FAP-expressing cells, accumulates in FAP-expressing tumor lesions, and shows low uptake in normal tissues except the kidneys. FAPI-34 is applicable for tumor-related research[1].
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FAPI-34 | 98.04% | FAPI-34 is a SPECT imaging agent targeting FAP. FAPI-34 specifically binds to FAP, is highly internalized by FAP-expressing cells, accumulates in FAP-expressing tumor lesions, and shows low uptake in normal tissues except the kidneys. FAPI-34 is applicable for tumor-related research. | ||||||||||||||||||||
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Keywords
