2376928-82-2
2376928-82-2
Chemical Structure
AXL-IN-13
- CAS No.: 2376928-82-2
- Formula:C34H41FN6O5
- Molecular Weight:632.72
IUPAC Name: N-cyclohexyl-3-((3-fluoro-4-((6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yl)oxy)phenyl)amino)-1-methyl-1H-pyrazole-4-carboxamide
InChIKey: QBRQTJMZEYORSP-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C2=C1)N=CC=C2OC3=C(C=C(C=C3)NC4=NN(C=C4C(NC5CCCCC5)=O)C)F)OCCCN6CCOCC6
Biological Activity: AXL-IN-13 is a potent and orally active AXL inhibitor (IC50: 1.6 nM, Kd: 0.26 nM). AXL-IN-13 reverses TGF-β1-induced epithelial-mesenchymal transition (EMT), and inhibits cancer cell migration and invasion[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AXL-IN-13 | 98.03% | AXL-IN-13 is a potent and orally active AXL inhibitor (IC50: 1.6 nM, Kd: 0.26 nM). AXL-IN-13 reverses TGF-β1-induced epithelial-mesenchymal transition (EMT), and inhibits cancer cell migration and invasion. | ||||||||||||||||||||
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References
Keywords
