2444-49-7
Chemical Structure
Diallyl tetrasulfide
- CAS No.: 2444-49-7
- Formula:C6H10S4
- Molecular Weight:210.40
IUPAC Name: 1,4-diallyltetrasulfane
InChIKey: RMKCQUWJDRTEHE-UHFFFAOYSA-N
SMILES: C=CCSSSSCC=C
Biological Activity: Diallyl tetrasulfide is an orally active diallyl tetrasulfide. Diallyl tetrasulfide ameliorates cadmium-induced changes in acetylcholinesterase and adenosine triphosphatase activities as well as oxidative stress injury in the brain of rats. Diallyl tetrasulfide inhibits lipid peroxidation in rat liver microsomes. Diallyl tetrasulfide ameliorates cadmium-induced oxidative liver injury in rats. Diallyl tetrasulfide protects cells against cadmium-induced loss of cell viability, reduces apoptosis rate and ROS production. Diallyl tetrasulfide is applicable to research related to cadmium-induced neurotoxicity and cadmium-induced oxidative liver injury[1][2][3][4].
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Diallyl tetrasulfide | Diallyl tetrasulfide is an orally active diallyl tetrasulfide. Diallyl tetrasulfide ameliorates cadmium-induced changes in acetylcholinesterase and adenosine triphosphatase activities as well as oxidative stress injury in the brain of rats. Diallyl tetrasulfide inhibits lipid peroxidation in rat liver microsomes. Diallyl tetrasulfide ameliorates cadmium-induced oxidative liver injury in rats. Diallyl tetrasulfide protects cells against cadmium-induced loss of cell viability, reduces apoptosis rate and ROS production. Diallyl tetrasulfide is applicable to research related to cadmium-induced neurotoxicity and cadmium-induced oxidative liver injury. | |||||||||||||||||||||
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- [1]. Pari L, et al. Diallyl tetrasulfide improves cadmium induced alterations of acetylcholinesterase, ATPases and oxidative stress in brain of rats. Toxicology. 2007;234(1-2):44-50. [Content Brief]
- [2]. Toshiharu Horie, et al. Identified Diallyl Polysulfides from an Aged Garlic Extract which Protects the Membranes from Lipid Peroxidation. Planta Med 1992; 58(5): 468-469.
- [3]. Murugavel P, et al. Effects of diallyl tetrasulfide on cadmium-induced oxidative damage in the liver of rats. Hum Exp Toxicol. 2007;26(6):527-534. [Content Brief]
- [4]. Murugavel P, et al. Cadmium induced mitochondrial injury and apoptosis in vero cells: protective effect of diallyl tetrasufide from garlic. Int J Biochem Cell Biol. 2007;39(1):161-170. [Content Brief]
Keywords
