2444302-23-0

HDAC6-IN-33 Chemical Structure
2444302-23-0

Chemical Structure

HDAC6-IN-33

  • CAS No.: 2444302-23-0
  • Formula:C14H11F2N5O
  • Molecular Weight:303.27

InChIKey: AWVDCEAYEQNKPT-UHFFFAOYSA-N

SMILES: FC(F)C(O1)=NN=C1C(C=N2)=CN=C2NCC3=CC=CC=C3

Biological Activity: HDAC6-IN-33 (compound 6) is a selective and irreversible HDAC6 inhibitor with an IC50 of 193 nM. HDAC6-IN-33 shows no activity against HDAC1-4. HDAC6-IN-33 is a tight-binding HDAC6 inhibitor capable of inhibiting HDAC6 via a two-step slow-binding mechanism[1].

Cat. No. Product Name Purity Description Pricing
HY-161304 		HDAC6-IN-33 98.96% HDAC6-IN-33 (compound 6) is a selective and irreversible HDAC6 inhibitor with an IC50 of 193 nM. HDAC6-IN-33 shows no activity against HDAC1-4. HDAC6-IN-33 is a tight-binding HDAC6 inhibitor capable of inhibiting HDAC6 via a two-step slow-binding mechanism.
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