2444302-23-0
Chemical Structure
HDAC6-IN-33
- CAS No.: 2444302-23-0
- Formula:C14H11F2N5O
- Molecular Weight:303.27
InChIKey: AWVDCEAYEQNKPT-UHFFFAOYSA-N
SMILES: FC(F)C(O1)=NN=C1C(C=N2)=CN=C2NCC3=CC=CC=C3
Biological Activity: HDAC6-IN-33 (compound 6) is a selective and irreversible HDAC6 inhibitor with an IC50 of 193 nM. HDAC6-IN-33 shows no activity against HDAC1-4. HDAC6-IN-33 is a tight-binding HDAC6 inhibitor capable of inhibiting HDAC6 via a two-step slow-binding mechanism[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HDAC6-IN-33 | 98.96% | HDAC6-IN-33 (compound 6) is a selective and irreversible HDAC6 inhibitor with an IC50 of 193 nM. HDAC6-IN-33 shows no activity against HDAC1-4. HDAC6-IN-33 is a tight-binding HDAC6 inhibitor capable of inhibiting HDAC6 via a two-step slow-binding mechanism. | ||||||||||||||||||||
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