2493978-38-2
2493978-38-2
Chemical Structure
TIM-063
- CAS No.: 2493978-38-2
- Formula:C18H9N3O4
- Molecular Weight:331.28
IUPAC Name: 2-hydroxy-3-nitro-7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
InChIKey: RDNQPAWXXJDVPO-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CC3=C([N+]([O-])=O)C(O)=CC(C4=NC5=C(N14)C=CC=C5)=C32
Biological Activity: TIM-063 is a selective and cell-permeable CaMKK inhibitor, ATP competitive inhibitor, can directly target the catalytic domain of CaMKK, with the Ki values of 0.35 μM and 0.2 μM for CaMKKα and CaMKKβ, respectively, the IC50 values are 0.63 μM and 0.96 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TIM-063 | 96.63% | TIM-063 is a selective and cell-permeable CaMKK inhibitor, ATP competitive inhibitor, can directly target the catalytic domain of CaMKK, with the Ki values of 0.35 μM and 0.2 μM for CaMKKα and CaMKKβ, respectively, the IC50 values are 0.63 μM and 0.96 μM, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.71
HY-19805STO-609 -
Similarity Score 0.69
HY-19805ASTO-609 acetate -
Similarity Score 0.68
HY-W338764AHR agonist 3 -
Similarity Score 0.63
HY-D1457DND-189 -
Similarity Score 0.62
HY-11843810-Cl-BBQ -
Similarity Score 0.58
HY-D0242Vat Red 15 -
Similarity Score 0.58
HY-D0457C.I. Solvent red 179 -
Similarity Score 0.50
HY-Q51222ZINC110492 -
Similarity Score 0.50
HY-N87845-Hydroxycanthin-6-one -
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