2503015-75-4
2503015-75-4
Chemical Structure
BPR1R024
- CAS No.: 2503015-75-4
- Formula:C24H21F3N6O2
- Molecular Weight:482.46
IUPAC Name: 1-(4-((7-(dimethylamino)quinazolin-4-yl)oxy)phenyl)-3-((6-(trifluoromethyl)pyridin-3-yl)methyl)urea
InChIKey: ORYMWWSJZRCUSV-UHFFFAOYSA-N
SMILES: CN(C1=CC2=C(C(OC3=CC=C(C=C3)NC(NCC4=CC=C(N=C4)C(F)(F)F)=O)=NC=N2)C=C1)C
Biological Activity: BPR1R024 is an orally active and selective colony-stimulating factor-1 receptor (CSF1R) inhibitor. BPR1R024 has potent CSF1R inhibition activity with an IC50 value of 0.53 nM. BPR1R024 can be used for the research of immuno-oncology[1].
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BPR1R024 | 98.50% | BPR1R024 is an orally active and selective colony-stimulating factor-1 receptor (CSF1R) inhibitor. BPR1R024 has potent CSF1R inhibition activity with an IC50 value of 0.53 nM. BPR1R024 can be used for the research of immuno-oncology. | ||||||||||||||||||||
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