2641595-54-0
2641595-54-0
Chemical Structure
Bivamelagon
Synonym(s): MC-4R Agonist 2
- CAS No.: 2641595-54-0
- Formula:C35H53ClN4O4
- Molecular Weight:629.27
InChIKey: QLOCFNAGHBVTJD-VYADMOTASA-N
SMILES: O=C([C@H]1[C@H](C2=CC=C(C=C2)Cl)CN(C1)C(C)(C)C)N3[C@@H](C[C@@H](C3)N([C@@H]4CC[C@@H](CC4)C)C(C(C)C)=O)C(N5CCOCC5)=O
Biological Activity: Bivamelagon (MC-4R Agonist 2) is an orally active MC4R agonist with EC50 values of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay), and a Ki of 65 nM. Bivamelagon can be used for the research of diseases such as obesity and diabetes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Bivamelagon | 99.19% | Bivamelagon (MC-4R Agonist 2) is an orally active MC4R agonist with EC50 values of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay), and a Ki of 65 nM. Bivamelagon can be used for the research of diseases such as obesity and diabetes. | ||||||||||||||||||||
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Bivamelagon-d8 | Bivamelagon-d8 (MC-4R Agonist 2-d8) is the deuterium labeled Bivamelagon (HY-153660). Bivamelagon (MC-4R Agonist 2) is an orally active MC4R agonist with EC50 values of 0.562 nM (Luci assay) and 36.5 nM (cAMP assay), and a Ki of 65 nM. Bivamelagon can be used for the research of diseases such as obesity and diabetes. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.99
HY-153660ABivamelagon hydrochloride -
Similarity Score 0.49
HY-111131RY764 -
Similarity Score 0.46
HY-11073MK-0489 -
Similarity Score 0.46
HY-161079TDI-8304 -
Similarity Score 0.45
HY-15114S 17092 -
Similarity Score 0.45
HY-U00339H3 receptor-MO-1 -
Similarity Score 0.44
HY-P5741IPL344 -
Similarity Score 0.44
HY-15519LBW242 -
Similarity Score 0.44
HY-111037BMS-457 -
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