2661609-36-3

DP-C-4 Chemical Structure
2661609-36-3

Chemical Structure

DP-C-4

  • CAS. Nr.: 2661609-36-3
  • Formula:C72H78ClF2N15O14
  • Molecular Weight:1450.93

IUPAC Name: 6-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-(3-((1-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)-1-((6-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-6-oxohexyl)amino)-1-oxopropan-2-yl)hexanamide

InChIKey: RXJUEWUXCCBXOG-UHFFFAOYSA-N

SMILES: O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(CCCCCNC(C(NC(CCCCCOC4=C(OC)C=C(N=CN=C5NC6=CC=C(F)C(Cl)=C6)C5=C4)=O)COCC7=CN(CCOCCOCCNC8=CC=CC(C(N9C%10CCC(NC%10=O)=O)=O)=C8C9=O)N=N7)=O)=O)CC3)=O)=C2)C%11=C1C=CC=C%11

Biological Activity: DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-141481
DP-C-4 98.15% DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References