2661609-36-3
Chemical Structure
DP-C-4
- CAS No.: 2661609-36-3
- Formula:C72H78ClF2N15O14
- Molecular Weight:1450.93
IUPAC Name: 6-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-(3-((1-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)-1-((6-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-6-oxohexyl)amino)-1-oxopropan-2-yl)hexanamide
InChIKey: RXJUEWUXCCBXOG-UHFFFAOYSA-N
SMILES: O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(CCCCCNC(C(NC(CCCCCOC4=C(OC)C=C(N=CN=C5NC6=CC=C(F)C(Cl)=C6)C5=C4)=O)COCC7=CN(CCOCCOCCNC8=CC=CC(C(N9C%10CCC(NC%10=O)=O)=O)=C8C9=O)N=N7)=O)=O)CC3)=O)=C2)C%11=C1C=CC=C%11
Biological Activity: DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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DP-C-4 | 98.15% | DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP. | ||||||||||||||||||||
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-
Similarity Score 0.67
HY-141486(Rac)-PROTAC PARP/EGFR ligand 1 -
Similarity Score 0.67
HY-141486APROTAC PARP/EGFR ligand 1 -
Similarity Score 0.60
HY-139156SK-575 -
Similarity Score 0.59
HY-181392PROTAC EZH2 Degrader-35 -
Similarity Score 0.58
HY-147101SK-575-NEG -
Similarity Score 0.57
HY-147941MS9427 -
Similarity Score 0.56
HY-180979P22D -
Similarity Score 0.56
HY-180977P19P -
Similarity Score 0.56
HY-141640MS154 -
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