26944-48-9
26944-48-9
Chemical Structure
Glibornuride
- CAS No.: 26944-48-9
- Formula:C18H26N2O4S
- Molecular Weight:366.48
IUPAC Name: N-(((1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)carbamoyl)-4-methylbenzenesulfonamide
InChIKey: RMTYNAPTNBJHQI-LLDVTBCESA-N
SMILES: O=S(C1=CC=C(C)C=C1)(NC(N[C@H]2[C@@](C3(C)C)([H])CC[C@@]3(C)[C@H]2O)=O)=O
Biological Activity: Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75[1]. Antidiabetic agent[2].
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Glibornuride | 98.92% | Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75. Antidiabetic agent. | ||||||||||||||||||||
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Glibornuride (Standard) | ≥98% | Glibornuride (Standard) is the analytical standard of Glibornuride. This product is intended for research and analytical applications. Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75. Antidiabetic agent. | ||||||||||||||||||||
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References
- [1]. Löffler C, et al. Pharmacological characterization of the sulphonylurea receptor in rat isolated aorta. Br J Pharmacol. 1997 Feb;120(3):476-80. [Content Brief]
- [2]. Ozsoy-Sacan O, et al. Effects of parsley (Petroselinum crispum) extract versus Glibornuride on the liver of streptozotocin-induced diabetic rats. J Ethnopharmacol. 2006 Mar 8;104(1-2):175-81. [Content Brief]
