1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Glibornuride


Cat. No.: HY-17451 Purity: 99.25%
COA Handling Instructions

Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75. Antidiabetic agent.

For research use only. We do not sell to patients.

Glibornuride Chemical Structure

Glibornuride Chemical Structure

CAS No. : 26944-48-9

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 253 In-stock
10 mM * 1 mL in DMSO USD 253 In-stock
5 mg USD 230 In-stock
10 mg USD 370 In-stock
25 mg USD 750 In-stock
50 mg USD 1280 In-stock
100 mg USD 1950 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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  • Purity & Documentation

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Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75[1]. Antidiabetic agent[2].

IC50 & Target

pKi: 5.75 (KATP channel)[1]

In Vivo

Administration of Glibornuride (5 mg/kg; gavage, daily for 28 days) for 28 days causes an increase in body weights in the diabetic groups in Swiss albino rats[2].
Treatment with Glibornuride for 28 days decreases the serum uric acid levels in diabetic rats[2].
Administration of Glibornuride for 28 days, insignificantly increases the liver lipid peroxidation levels in diabetic rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-6.5-month-old male Swiss Albino rats, weighing 150-200 g[2]
Dosage: 5 mg/kg
Administration: Given by gavage, daily for 28 days
Result: Administration for 28 days caused an increase in body weights in the diabetic groups.
Treatment for 28 days decreased the serum uric acid levels in diabetic rats.
Molecular Weight







White to off-white




Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (682.17 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7287 mL 13.6433 mL 27.2866 mL
5 mM 0.5457 mL 2.7287 mL 5.4573 mL
10 mM 0.2729 mL 1.3643 mL 2.7287 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.08 mg/mL (5.68 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.08 mg/mL (5.68 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
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Glibornuride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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