2770960-52-4
2770960-52-4
Chemical Structure
BIIB129
- CAS No.: 2770960-52-4
- Formula:C19H22N6O2
- Molecular Weight:366.42
InChIKey: WBFSPPPOPIJCLF-DHFPXDALSA-N
SMILES: CN(N=C1)C=C1C2=CN3C(C(O[C@]4(C[C@H](C4)N(C)C(C=C)=O)C)=N2)=CC=N3
Biological Activity: BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK, thereby affecting the function of B cells and myeloid cells. BIIB129 can be used in multiple sclerosis (MS) research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BIIB129 | 99.54% | BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier. BIIB129 inhibits the activity of BTK by covalently binding to Cys481 in BTK, thereby affecting the function of B cells and myeloid cells. BIIB129 can be used in multiple sclerosis (MS) research. | ||||||||||||||||||||
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References
Keywords
