2814486-79-6
2814486-79-6
Chemical Structure
DYRK1-IN-1
- CAS No.: 2814486-79-6
- Formula:C12H12N6
- Molecular Weight:240.26
IUPAC Name: N,N-dimethyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine
InChIKey: IFLBFWBMAWIBBZ-UHFFFAOYSA-N
SMILES: CN(C1=NC(C2=C3C=CC=NN3N=C2)=CC=N1)C
Biological Activity: DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. DYRK1-IN-1 can be used for the research of central nervous system penetrant DYRK1A chemical probe[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DYRK1-IN-1 | 99.71% | DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. DYRK1-IN-1 can be used for the research of central nervous system penetrant DYRK1A chemical probe. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-183529Antitrypanosomal agent 31 -
Similarity Score 0.71
HY-147060Dyrk1A-IN-3 -
Similarity Score 0.64
HY-128491UNC10112785 -
Similarity Score 0.60
HY-114567GW780056X -
Similarity Score 0.57
HY-788663-(2-ChloropyriMidin-4-yl)-1-methylindole -
Similarity Score 0.56
HY-W013852PKC-IN-6 -
Similarity Score 0.56
HY-W107409Meridianin C -
Similarity Score 0.56
HY-123369BMI-1026 -
Similarity Score 0.55
HY-W809647CDK modulator 1 -
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