28230-32-2
28230-32-2
Chemical Structure
HODHBt
Synonym(s): HOOBt
- CAS No.: 28230-32-2
- Formula:C7H5N3O2
- Molecular Weight:163.13
IUPAC Name: 3-hydroxybenzo[d][1,2,3]triazin-4(3H)-one
InChIKey: HJBLUNHMOKFZQX-UHFFFAOYSA-N
SMILES: O=C1N(O)N=NC2=CC=CC=C12
Biological Activity: HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
HODHBt | 99.34% | HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
