2832159-84-7
Chemical Structure
DS01080522
- CAS. Nr.: 2832159-84-7
- Formula:C23H20Cl2N4O3
- Molecular Weight:471.34
IUPAC Name: 1-chloro-N-((S)-(3-chloro-4-cyanophenyl)((2R,4S)-4-hydroxypyrrolidin-2-yl)methyl)-7-methoxyisoquinoline-6-carboxamide
InChIKey: UUZDBTHUOQZIJF-DLVCFXQMSA-N
SMILES: O=C(N[C@H]([C@@]1([H])C[C@H](O)CN1)C2=CC(Cl)=C(C#N)C=C2)C3=CC4=CC=NC(Cl)=C4C=C3OC
Biological Activity: DS01080522 is a Protein Kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor. DS01080522 inhibits PRKACA kinase activity and CREB phosphorylation with IC50s of 0.8 nM and 66 nM, respectively. DS01080522 can be used for the research of cancer[1].
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DS01080522 | DS01080522 is a Protein Kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor. DS01080522 inhibits PRKACA kinase activity and CREB phosphorylation with IC50s of 0.8 nM and 66 nM, respectively. DS01080522 can be used for the research of cancer. | |||||||||||||||||||||
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Keywords
