2906872-59-9
Chemical Structure
NLRP3-IN-16
- CAS No.: 2906872-59-9
- Formula:C25H25NO5
- Molecular Weight:419.47
IUPAC Name: (S)-11-(1,5-dihydroxypentan-2-yl)-3-methyl-9,10,11,12-tetrahydrophenanthro[2',1':4,5]furo[2,3-c]pyridine-7,8-dione
InChIKey: IZYGWVLDEVWNOE-HNNXBMFYSA-N
SMILES: CC1=C2C=CC3=C(C2=CC=C1)C(C(C4=C3OC5=C4CCN(C5)[C@@H](CCCO)CO)=O)=O
Biological Activity: NLRP3-IN-16 is a potent and selective NLRP3 inflammasome inhibitor. NLRP3-IN-16 inhibits IL-1β release with an IC50 of 0.065 μM. NLRP3-IN-16 can be used for the research of inflammation[1].
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NLRP3-IN-16 | NLRP3-IN-16 is a potent and selective NLRP3 inflammasome inhibitor. NLRP3-IN-16 inhibits IL-1β release with an IC50 of 0.065 μM. NLRP3-IN-16 can be used for the research of inflammation. | |||||||||||||||||||||
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Keywords