2913161-19-8

ACBI2 Chemical Structure
2913161-19-8

Chemical Structure

ACBI2

  • CAS No.: 2913161-19-8
  • Formula:C56H68BrFN8O5S
  • Molecular Weight:1064.16

IUPAC Name: N-(4-bromo-2,3-dichlorophenyl)-6-(2,3-dimethylphenyl)pyrazin-2-amine

InChIKey: JBTHUOYYUUPUOZ-LIHPQFRDSA-N

SMILES: BrC1=CC=CC(N(C2=CC=C(C3CCN(CC[C@@H](C)CC[C@@H](C4=CC=C(C5=C(C)N=CS5)C=C4)NC([C@@H]6C[C@@H](O)CN6C([C@H](C(C)(C)C)NC(C7(CC7)F)=O)=O)=O)CC3)C=C2N8C9CCCC9)C8=N%10)=C1C%10=O

Biological Activity: ACBI2 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-151623 		ACBI2 99.38% ACBI2 is a highly potent and orally active VHL PROTAC SMARCA2 degrader (EC50: 7 nM), which selectively degrades SMARCA2 with a DC50 value of 1 nM in RKO cells. ACBI2 can be used in the research of lung cancer.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

Keywords