2999673-52-6
2999673-52-6
Chemical Structure
ZG297
- CAS No.: 2999673-52-6
- Formula:C31H35F3N4O3
- Molecular Weight:568.63
InChIKey: LRRHDBKPDZEZJJ-GFNGZDJJSA-N
SMILES: FC(F)(F)CCCNC(N1[C@](CN(CC2=CC(C=CC=C3)=C3C4=C2C=CC=C4)C([C@@H]5[C@H](CC)C)=O)([H])N5C(CC1)=O)=O
Biological Activity: ZG297 is an agonist for Staphylococcus aureus ClpP (SaClpP ) with an EC50 of 0.26 μM. ZG297 degrades SaFtsZ, inhibits the bacterial cell division, thereby exhibiting antistaphylococcal activity, that inhibits S. aureus 8325-4 strains and MRSA strains with MIC of 0.063-256 μg/mL. ZG297 exhibits anti-infectious efficacy in mouse models[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ZG297 | 99.69% | ZG297 is an agonist for Staphylococcus aureus ClpP (SaClpP ) with an EC50 of 0.26 μM. ZG297 degrades SaFtsZ, inhibits the bacterial cell division, thereby exhibiting antistaphylococcal activity, that inhibits S. aureus 8325-4 strains and MRSA strains with MIC of 0.063-256 μg/mL. ZG297 exhibits anti-infectious efficacy in mouse models. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.81
HY-186109ZY39 -
Similarity Score 0.76
HY-152096(R)-ZG197 -
Similarity Score 0.76
HY-152097(S)-ZG197 -
Similarity Score 0.71
HY-155556ZG36 -
Similarity Score 0.59
HY-14428ICG-001 -
Similarity Score 0.47
HY-16946CP-610431 -
Similarity Score 0.46
HY-138059SM-433 -
Similarity Score 0.46
HY-124181SM-1295 -
Similarity Score 0.45
HY-13208Xevinapant hydrochloride -
Explore the MedChemAI to find more analogs
