2999673-52-6
Chemical Structure
ZG297
- CAS No.: 2999673-52-6
- Formula:C31H35F3N4O3
- Molecular Weight:568.63
InChIKey: LRRHDBKPDZEZJJ-GFNGZDJJSA-N
SMILES: FC(F)(F)CCCNC(N1[C@](CN(CC2=CC(C=CC=C3)=C3C4=C2C=CC=C4)C([C@@H]5[C@H](CC)C)=O)([H])N5C(CC1)=O)=O
Biological Activity: ZG297 is an agonist for Staphylococcus aureus ClpP (SaClpP ) with an EC50 of 0.26 μM. ZG297 degrades SaFtsZ, inhibits the bacterial cell division, thereby exhibiting antistaphylococcal activity, that inhibits S. aureus 8325-4 strains and MRSA strains with MIC of 0.063-256 μg/mL. ZG297 exhibits anti-infectious efficacy in mouse models[1].
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ZG297 | 99.69% | ZG297 is an agonist for Staphylococcus aureus ClpP (SaClpP ) with an EC50 of 0.26 μM. ZG297 degrades SaFtsZ, inhibits the bacterial cell division, thereby exhibiting antistaphylococcal activity, that inhibits S. aureus 8325-4 strains and MRSA strains with MIC of 0.063-256 μg/mL. ZG297 exhibits anti-infectious efficacy in mouse models. | ||||||||||||||||||||
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Keywords