302912-05-6
302912-05-6
Chemical Structure
DL-Dithiothreitol-d10
Synonym(s): DTT-d10
- CAS No.: 302912-05-6
- Formula:C4D10O2S2
- Molecular Weight:164.31
IUPAC Name: 2-((2-((4-acrylamido-2-methoxyphenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide
InChIKey: VHJLVAABSRFDPM-BSSDICLPSA-N
SMILES: [2H]SC([2H])([2H])C(O[2H])([2H])C(O[2H])([2H])C([2H])([2H])S[2H]
Biological Activity: DL-Dithiothreitol-d10 is the deuterated form of DL-Dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond[1][2].
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DL-Dithiothreitol-d10 | 98.4% | DL-Dithiothreitol-d10 is the deuterated form of DL-Dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond. | ||||||||||||||||||||
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DL-Dithiothreitol-d10-1 | DL-Dithiothreitol-d10-1 is the deuterated form of DL-dithiothreitol. DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-Dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond. | |||||||||||||||||||||
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DL-Dithiothreitol-d6 | 98.73% | DL-Dithiothreitol-d6 is the deuterated form of DL-Dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond. | ||||||||||||||||||||
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DL-Dithiothreitol | 98.31% | DL-Dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-Dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24(1): 183. [Content Brief]
