3036751-77-3

Antitumor agent-151 Chemical Structure
3036751-77-3

Chemical Structure

Antitumor agent-151

  • CAS No.: 3036751-77-3
  • Formula:C22H20FN5O
  • Molecular Weight:389.43

InChIKey: BQHRFHUEHRHTBI-UHFFFAOYSA-N

SMILES: O=C(C1=C(CCN(C1)CC2=CC(C#N)=CC=C2)N3)N=C3NCC4=CC=C(C=C4)F

Biological Activity: Antitumor agent-151 (7k) is a significant HsClpP agonist and an antileukemia drug candidate. Antitumor agent-151 (7k) exhibits remarkably enhanced proteolytic activity of HsClpP (EC50 = 0.79 μM) and antitumor activity in vitro (IC50 = 0.038 μM). Antitumor agent-151 (7k) induces apoptosis[1].

Cat. No. Product Name Purity Description Pricing
HY-162462 		Antitumor agent-151 Antitumor agent-151 (7k) is a significant HsClpP agonist and an antileukemia drug candidate. Antitumor agent-151 (7k) exhibits remarkably enhanced proteolytic activity of HsClpP (EC50 = 0.79 μM) and antitumor activity in vitro (IC50 = 0.038 μM). Antitumor agent-151 (7k) induces apoptosis.
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