3052257-09-4
3052257-09-4
Chemical Structure
NF-κB-IN-10
- CAS No.: 3052257-09-4
- Formula:C26H32N2O4
- Molecular Weight:436.54
InChIKey: FVMAINXPYRMNLG-DHZHZOJOSA-N
SMILES: CC(N1N=C(C)CC1C2=C(OC)C=C(OC)C=C2/C=C/C3=CC=C(OCCCC)C=C3)=O
Biological Activity: NF-κB-IN-10 (compound E1) is an NF-κB inhibitor that can improve heart failure by reducing oxidative stress and inflammation by regulating Nrf2/NF-κB signaling pathway. NF-κB-IN-10 inhibits LPS-induced NO production and expression of iNOS and COX-2 in RAW264.7 cells. NF-κB-IN-10 can be used in the research of cardiovascular diseases[1].
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NF-κB-IN-10 | NF-κB-IN-10 (compound E1) is an NF-κB inhibitor that can improve heart failure by reducing oxidative stress and inflammation by regulating Nrf2/NF-κB signaling pathway. NF-κB-IN-10 inhibits LPS-induced NO production and expression of iNOS and COX-2 in RAW264.7 cells. NF-κB-IN-10 can be used in the research of cardiovascular diseases. | |||||||||||||||||||||
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