3059617-75-0
Chemical Structure
CYP51-IN-36
- CAS No.: 3059617-75-0
- Formula:C12H10ClN3O2
- Molecular Weight:263.68
SMILES: O=C(C1=NC=CN1C)O/N=C/C2=CC=C(Cl)C=C2
Biological Activity: CYP51-IN-36 is a CYP51 inhibitor and Antifungal agent. CYP51-IN-36 inhibits Ergosterol (HY-N0181) biosynthesis, induces intracellular ROS accumulation, disrupts mitochondrial function and causes mitochondrial membrane potential depolarization, impairs nuclear integrity, increases plasma membrane permeability and leads to electrolyte leakage, and inhibits SOD and POD antioxidant defense enzyme activities. CYP51-IN-36 exhibits antifungal activity against Botrytis cinerea, Rhizoctonia solani, Valsa mali and Sclerotinia sclerotiorum, and shows protective and disease control activity against Botrytis cinerea[1].
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CYP51-IN-36 | CYP51-IN-36 is a CYP51 inhibitor and Antifungal agent. CYP51-IN-36 inhibits Ergosterol (HY-N0181) biosynthesis, induces intracellular ROS accumulation, disrupts mitochondrial function and causes mitochondrial membrane potential depolarization, impairs nuclear integrity, increases plasma membrane permeability and leads to electrolyte leakage, and inhibits SOD and POD antioxidant defense enzyme activities. CYP51-IN-36 exhibits antifungal activity against Botrytis cinerea, Rhizoctonia solani, Valsa mali and Sclerotinia sclerotiorum, and shows protective and disease control activity against Botrytis cinerea. | |||||||||||||||||||||
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